NON-INVASIVE TRANSDERMAL DRUG DELIVERY
ExplanationIontophoresis uses a weak electronic direct current to introduce drugs through intact skin to the underlying tissue. The drug is introduced directly into the area to be treated – a kind of pharmacological sharpshooting. This reduces the effects on the system to a minimum, and no side effects have been reported. Iontophoresis is an effective, painless treatment method.
The technology is based on the principle that ions in a solution begin to travel when exposed to electrical stimulation, depending on their charge. The drug delivery electrode is connected to the same polarity as the charge of the drug’s ion, which causes the system to repel the drug ion, pressing it through the skin.
There are two primary treatment areas for iontophoresis today: For cortisone treatment of shallow, local inflammations, and as a quick and effective way to apply a topical anesthetic.
Drugs used in iontophoresis treatment must be water-soluble and ionized.
Iontophoresis treatment requires top-quality equipment. The electrodes must distribute the current evenly over the whole surface, and be manufactured in such a way as to effectively deliver the specific drug.